The rate of infertility has increased
globally over the years, due to various reasons. Given the psychosocial
implications of infertility and its effects on the life of the affected people,
there has been an increased focus on its treatment over the last several years.
Assisted reproductive technology can only solve about 50% of the cases.
Moreover, it contains significant risks and does not solve the fundamental
problem of infertility. As pluripotent stem cells have the potential to
differentiate into almost any type of cell, they have been widely regarded as a
promising option in the development of stem cell-based fertility treatments,
which could even correct genetic diseases in offspring. These advancements in
reproductive biotechnology present both challenges and possibilities for
solving infertility problems caused by various unexplainable factors.
The committed stem and progenitor cells have
been recently isolated from various adult tissues, including hematopoietic stem
cell, neural stem cell, mesenchymal stem cell and endothelial progenitor cell.
These adult stem cells have several advantages as compared with embryonic stem
cells as their practical therapeutic application for tissue regeneration.
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